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// 02 Highlighted

Highlighted publications

  • 2025
    Global evolution of inflammatory bowel disease across epidemiologic stagesLindsay Hracs, Joseph W. Windsor, Julia Gorospe ... Bobby Zhao Sheng Lo ... · Nature

    Using a century of global data, researchers mapped the progression of inflammatory bowel disease through three stages and modeled a proposed fourth stage.

  • 2018
    Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled studySofie Ingdam Halkjær, Alice Højer Christensen, Bobby Zhao Sheng Lo ... · Gut

    Fecal transplants changed gut bacteria in IBS patients, but placebo capsules led to greater symptom improvement.

  • 2018
    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsiesMette Boyd, Malte Thodberg, Morana Vitezic ... Bobby Zhao Sheng Lo ... · Nature Communications

    By profiling colon tissue from 94 people, researchers found that just 35 gene-regulating sites can distinguish Crohn’s disease, ulcerative colitis, and healthy controls with 85% accuracy.

  • 2020
    The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort StudiesBobby Zhao Sheng Lo, Mirabella Zhao, Ida Vind ... · Clinical Gastroenterology and Hepatology
  • 2018
    A 10-Year Follow-up Study of the Natural History of Perianal Crohn’s Disease in a Danish Population-Based Inception CohortMirabella Zhao, Bobby Zhao Sheng Lo, Marianne Kajbæk Vester-Andersen ... · Inflammatory Bowel Diseases

    A study on Crohn's patients revealed that perianal disease increases long-term risks of surgery and hospitalization, signaling a more severe disease course.

// 03 All publications

Peer-reviewed publications

This publication list is generated automatically from OpenAlex and may contain occasional errors or omissions.

  • 2026
    Deep Learning‐Based Automated Bowel Wall Thickness Measurement in Intestinal Ultrasound for Inflammatory Bowel DiseaseJakob Hestbjerg Karrer, Jonatan Ruiz-Molsgaard, Bjørn Leth Møller, Johan Burisch, Gorm Roager Madsen, Klaus Theede, Johan Fremberg Ilvemark, Bobby Zhao Sheng Lo, Bulat Ibragimov, Trine Boysen · JCC Plus

    An AI system tested for measuring bowel wall thickness on intestinal ultrasound scans of inflammatory bowel disease patients produced measurements that closely matched those of medical experts.

  • 2026
    Changes in nasal and throat microbiota composition during and after mupirocin and chlorhexidine decolonization treatment in asymptomatic methicillin-resistant Staphylococcus aureus carriers: a longitudinal observational studySofie Marie Edslev, Cindy Meng-Hsin Liu, Bobby Zhao Sheng Lo, Heidi Meiniche, Berit Lilje, Daniel K. Park, Amalie Katrine Rendboe, Tony Pham, Juan E. Salazar, Tor Toudahl, Anna Cäcilia Ingham, Maliha Aziz, Mette Damkjær Bartels, Paal Skytt Andersen, Robert Leo Skov, Lance Bradley Price, Marc Stegger · Clinical Microbiology and Infection

    Testing a standard MRSA decolonization treatment showed that while it successfully cleared the bacteria in most carriers, it also caused long-lasting disruptions to their nasal microbiomes.

  • 2025
    AI-BUS: AI Bowel Ultrasound SystemJonatan Ruiz-Molsgaard, Jakob Karrer, Bobby Zhao Sheng Lo, Bjørn Leth Møller, Gorm Roager Madsen, J F K F Ilvemark, Klaus Theede, Johan M. Burisch, Bulat Ibragimov, Trine Boysen · EMJ Gastroenterology
  • 2025
    Clinical Trial: Evaluating a Single 1600 mg Tablet Regimen of 5‐Aminosalicylate for Ulcerative Colitis—The EASI TrialRie Louise Møller Nordestgaard, Bobby Zhao Sheng Lo, Reinhold Bergström, Izabella Adzioski, Helene Skotte, Ida Marie Hawwa, Signe Krogsgaard Holme, Bermal Tiftikci, Katarzyna Majchrzak, Ida Vind, Flemming Bendtsen, Johan M. Burisch · Alimentary Pharmacology & Therapeutics

    A clinical trial comparing a single daily tablet for ulcerative colitis to three tablets found that both treatments resulted in similar patient adherence and disease relapse rates.

  • 2025
    Incidence and Long‐Term Outcomes of Pouchitis in Ulcerative Colitis PatientsReinhold Bergström, Bobby Zhao Sheng Lo, Eva Toft, Sebastian Schmidt, Stefan Kaiser, Robert Kudernatsch, Orhan Bulut, Flemming Bendtsen, Johan M. Burisch · United European Gastroenterology Journal

    A study of ulcerative colitis patients after pouch surgery found that half experienced pouchitis, but urgent surgery did not increase this risk, and overall pouch failure was low.

  • 2025
    The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative studySimon Robert Knowles, Richard Blair Gearry, Megan L. Petrik, Sharon Jedel, Pragalathan Apputhurai, Bobby Zhao Sheng Lo, Gabriele Moser, Manuel Barreiro-de Acosta, Dan Lucian Dumitrascu, Nuno Bravo Ferreira, Floor Bennebroek Evertsz, Andreas Stengel, Johan M. Burisch, Anna Mokrowiecka, Alexander Charles Ford, Miranda A.L. van Tilburg, Inês A. Trindade, Charles Noah Bernstein, Lesley A. Graff, Antonina A Mikocka‐Walus · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  • 2025
    49: THE INCIDENCE AND PREVALENCE OF INFLAMMATORY BOWEL DISEASE IN NINE NATIONS ACROSS THE GLOBE: AN ANALYSIS OF THE 3RD EPIDEMIOLOGIC STAGE.Stephanie B. Coward, Joseph W. Windsor, Lindsay Hracs, Julia Gorospe, Antonio Aviña-Zubieta, Eric I. Benchimol, Charles Noah Bernstein, Alain M. Bitton, Eduard Brunet, Johan M. Burisch, Xavier Calvet, Gili Focht, Angela J. Forbes, Anders Forss, Richard Blair Gearry, Gareth‐Rhys Jones, Ellen Kuenzig, Peter Laszlo Lakatos, Charlie W. Lees, Berkeley N. Limketkai, Bobby Zhao Sheng Lo, Edward V. Loftus, Jonas Filip Ludvigsson, Siew C. Ng, Ola Olén, Anthony R. Otley, Remo Panaccione, Juan Nicolás Peña-Sánchez, Dan Turner, Emili Vela, Gilaad G. Kaplan · Gastroenterology
  • 2025
    Global evolution of inflammatory bowel disease across epidemiologic stagesLindsay Hracs, Joseph W. Windsor, Julia Gorospe, Michael Cummings, Stephanie B. Coward, Michael J. Buie, Joshua Quan, Quinn Goddard, Léa Caplan, Ante Markovinović, Tyler S. Williamson, Yvonne Abbey, Murdani Abdullah, María T. Abreu, Vineet Ahuja, Raja Affendi Raja Ali, Mansour A. Altuwaijri, Domingo Cesar Balderramo, Rupa Banerjee, Eric I. Benchimol, Charles Noah Bernstein, Eduard Brunet, Johan M. Burisch, Vui Heng Chong, Iris Dotan, Usha Dutta, Sara El Ouali, Angela J. Forbes, Anders Forss, Richard Blair Gearry, Hang Viet Dao, Juanda Leo Hartono, Ida Normiha Hilmi, Phoebe Hodges, Gareth‐Rhys Jones, Fabián Juliao Baños, Jamilya A. Kaibullayeva, Paul M. Kelly, Taku Kobayashi, Paulo Gustavo Kotze, Peter Laszlo Lakatos, Charlie W. Lees, Julajak Limsrivilai, Bobby Zhao Sheng Lo, Edward V. Loftus, Jonas Filip Ludvigsson, Joyce Wing Yan Mak, Yinglei Miao, Ka Kei Ng, Shinji Okabayashi, Ola Olén, Remo Panaccione, Mukesh Sharma Paudel, Abel Botelho Quaresma, David T. Rubin, Marcellus Simadibrata, Yang Sun, Hidekazu Suzuki, Martín Toro, Dan Turner, Beatriz Iade, Shu‐Chen Wei, Jesús K. Yamamoto‐Furusho, Suk‐Kyun Yang, Siew C. Ng, Gilaad G. Kaplan · Nature

    Using a century of global data, researchers mapped the progression of inflammatory bowel disease through three stages and modeled a proposed fourth stage.

  • 2025
    Improving the Real-Time Classification of Disease Severity in Ulcerative Colitis: Artificial Intelligence as the Trigger for a Second OpinionBobby Zhao Sheng Lo, Bjørn Leth Møller, Christian Igel, Signe Wildt, Ida Vind, Flemming Bendtsen, Johan M. Burisch, Bulat Ibragimov · The American Journal of Gastroenterology

    An AI system tested for classifying ulcerative colitis severity from endoscopy videos matched expert accuracy and improved the diagnostic performance of non-specialist doctors.

  • 2025
    P0290 Predicting disease remission in Ulcerative Colitis patients - early results from the PRESAGER studyRie Louise Møller Nordestgaard, Bobby Zhao Sheng Lo, Reinhold Bergström, Izabella Adzioski, Henriette Svarre Nielsen, Ida Marie Hawwa, Signe Krogsgaard Holme, Bermal Tiftikci, Krzysztof Majchrzak, Ida Vind, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    This study analyzed predictors of ulcerative colitis remission, finding that older age and higher disability reduced its likelihood, while longer disease duration and moderate activity increased it.

  • 2024
    Clinical Outcomes After First-Line Anti- Tumor-Necrosis-Factor Treatment of Patients With Inflammatory Bowel Disease—A Prospective Multicenter Cohort StudyMirabella Zhao, Lone Larsen, Anders Kirch Dige, Anja Poulsen, Bobby Zhao Sheng Lo, Mohamed Attauabi, Pernille Dige Ovesen, Mads Damsgaard Wewer, Dagmar Christiansen, Christian Lodberg Hvas, Andreas Munk Petersen, Flemming Bendtsen, Jakob Benedict Seidelin, Johan M. Burisch · Journal of Crohn s and Colitis

    Testing anti-TNF therapy in patients with inflammatory bowel disease showed that while most responded initially, about a quarter to a third eventually lost response during maintenance therapy.

  • 2024
    Histological, But Neither Clinical Nor Endoscopic Activity Predicts the Risk of Colectomy in Patients With Ulcerative Colitis Treated With BiologicsMirabella Zhao, Lene Buhl Riis, Bobby Zhao Sheng Lo, Mohamed Attauabi, Pernille Dige Ovesen, Mads Damsgaard Wewer, Lone Larsen, Anders Kirch Dige, Christian Lodberg Hvas, Anja Poulsen, Dagmar Christiansen, Zainab Gassem Nagras, Pernille Dahlin, Andreas Munk Petersen, Flemming Bendtsen, Jakob Benedict Seidelin, Johan M. Burisch · Inflammatory Bowel Diseases

    A study of ulcerative colitis patients starting biological therapy found that severe baseline tissue inflammation, but not endoscopic activity, independently predicts a higher risk of colon removal.

  • 2024
    Probiotic Treatment of Ulcerative Colitis with Trichuris Suis Ova: A Randomised, Double-blinded, Placebo-controlled Clinical Trial [the PROCTO Trial]Michelle V Prosberg, Sofie Ingdam Halkjær, Bobby Zhao Sheng Lo, Christina Bremerskov-Köser, J F K F Ilvemark, Jakob Benedict Seidelin, Malene Fey Kristiansen, Anja Kort, Thomas Kallemose, Peter Bager, Flemming Bendtsen, Inge Nordgaard-Lassen, Hanne Schultz Kapel, Helene Kringel, Christian M. O. Kapel, Andreas Munk Petersen · Journal of Crohn s and Colitis

    A clinical trial testing Trichuris suis ova for moderate ulcerative colitis found that the treatment was not superior to placebo in achieving clinical remission at 24 weeks.

  • 2024
    Building an AI Support Tool for Real-Time Ulcerative Colitis DiagnosisBjørn Leth Møller, Bobby Zhao Sheng Lo, Johan M. Burisch, Flemming Bendtsen, Ida Vind, Bulat Ibragimov, Christian Igel · Künstliche Intell.
  • 2024
    Specific Antibiotics Increase the Risk of Flare-Ups in Patients with Inflammatory Bowel Disease: Results from a Danish Nationwide Population-Based Nested Case-Control StudyBobby Zhao Sheng Lo, Luc Biederman, Gerhard Rogler, Barbara Dora, Andrea Kreienbühl, Ida Vind, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    A study of Danish patients found that using specific classes of antibiotics is associated with a significantly increased risk of inflammatory bowel disease flare-ups.

  • 2024
    The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic StagesGilaad G. Kaplan, Lindsay Hracs, Joseph W. Windsor, Julia Gorospe, K. Michael Cummings, Stephanie B. Coward, Michael J. Buie, Joshua Quan, Quinn Goddard, Léa Caplan, Ante Markovinović, Tyler S. Williamson, Yvonne Abbey, Murdani Abdullah, María T. Abreu, Vineet Ahuja, Raja Affendi Raja Ali, Mansour A. Altuwaijri, Domingo Cesar Balderramo, Rupa Banerjee, Eric I. Benchimol, Charles Noah Bernstein, Eduard Brunet, Johan M. Burisch, Vui Heng Chong, Iris Dotan, Usha Dutta, Sara El Ouali, Angela J. Forbes, Anders Forss, Richard Blair Gearry, Hang Viet Dao, Juanda Leo Hartono, Ida Normiha Hilmi, Phoebe Hodges, Gareth‐Rhys Jones, Fabián Juliao Baños, Jamilya A. Kaibullayeva, Paul M. Kelly, Taku Kobayashi, Paulo Gustavo Kotze, Peter Laszlo Lakatos, Charlie W. Lees, Julajak Limsrivilai, Bobby Zhao Sheng Lo, Edward V. Loftus, Jonas Filip Ludvigsson, Joyce Wing Yan Mak, Yinglei Miao, Ka Kei Ng, Shinji Okabayashi, Ola Olén, Remo Panaccione, Mukesh Sharma Paudel, Abel Botelho Quaresma, David T. Rubin, Marcellus Simadibrata, Yang Sun, Hidekazu Suzuki, Martín Toro, Dan Turner, Beatriz Vergara, Shu Chen Wei, Jesús K. Yamamoto‐Furusho, Suk‐Kyun Yang, Siew C. Ng · Research Square

    Analyzing a century of global data, researchers mapped how inflammatory bowel disease transitions through distinct epidemiological stages, confirming its progression from low incidence to compounding prevalence.

  • 2024
    P1174 The disease course of elderly patients with Inflammatory Bowel Disease two years prior to their deathKrzysztof Majchrzak, Bobby Zhao Sheng Lo, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    By examining elderly inflammatory bowel disease patients before death, researchers found that hospitalizations, corticosteroid prescriptions, and disease relapses spiked during the final two months of life.

  • 2024
    P598 Validating and Enhancing Real-time Disease Severity Classification in Ulcerative Colitis: Artificial Intelligence as a Second Opinion TriggerBobby Zhao Sheng Lo, Bjørn Leth Møller, Christian Igel, Signe Wildt, Ida Vind, Flemming Bendtsen, Johan M. Burisch, I Bulat · Journal of Crohn s and Colitis

    An AI model tested for evaluating ulcerative colitis severity from endoscopy videos matched expert accuracy and improved the diagnostic performance of non-specialist doctors.

  • 2024
    P1240 Systematic review with meta-analysis: faecal microbiota transplantation as treatment of chronic pouchitisFrederik Cold, Sofie Ingdam Halkjær, Bobby Zhao Sheng Lo, Kasper Glerup Lauridsen, Sabrina Just Kousgaard, Ole Thorlacius‐Ussing, Andreas Munk Petersen · Journal of Crohn s and Colitis

    A systematic review found that fecal microbiota transplantation was no more effective than a placebo at improving short-term symptoms in patients with chronic pouchitis.

  • 2024
    P375 Histological activity predicts the risk of colectomy after biological treatment in biological-naive patients with Ulcerative ColitisMirabella Zhao, Lene Buhl Riis, Bobby Zhao Sheng Lo, Mohamed Attauabi, Pernille Dige Ovesen, Mads Damsgaard Wewer, Lone Larsen, Anders Kirch Dige, Christian Lodberg Hvas, Anja Poulsen, D Christiansen, Zainab Gassem Nagras, Pernille Dahlin, Andreas Munk Petersen, Flemming Bendtsen, Jakob Benedict Seidelin, Johan M. Burisch, The Danish IBD Biobank Project Group · Journal of Crohn s and Colitis

    Testing ulcerative colitis patients starting biological therapy, researchers found that baseline gut tissue inflammation significantly predicted the risk of colon removal, while clinical and endoscopic symptoms did not.

  • 2023
    Fecal microbiota transplantation for the treatment of irritable bowel syndrome: A systematic review and meta-analysisSofie Ingdam Halkjær, Bobby Zhao Sheng Lo, Frederik Cold, Alice Højer Christensen, Savanne Holster, Julia König, Robert J. Brummer, Olga C. Aroniadis, Perttu Lahtinen, Tom Holvoet, Lise Lotte Gluud, Andreas Munk Petersen · World Journal of Gastroenterology

    A review of fecal microbiota transplantation for irritable bowel syndrome found insufficient evidence to support its use, as it did not significantly improve symptoms compared to a placebo.

  • 2023
    Tu1715 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL ON EFFICACY AND SAFETY OF PROBIOTIC TREATMENT WITH TRICHURIS SUIS OVA IN PATIENTS WITH ULCERATIVE COLITISMichelle V. Prosberg, Sofie Ingdam Halkjær, Bobby Zhao Sheng Lo, Christina B. Köser, J F K F Ilvemark, Jakob Benedict Seidelin, Malene F. Kristiansen, Anja Kort, Thomas Kallemose, Inge Nordgaard-Lassen, Peter Bager, Flemming Bendtsen, Hanne Schultz Kapel, Helene Kringel, Christian M. O. Kapel, Andreas Munk Petersen · Gastroenterology
  • 2023
    Identifying patients with inflammatory bowel disease in the Danish National Patient Register.Bobby Zhao Sheng Lo, Mirabella Zhao, Johan M. Burisch · PubMed

    Researchers tested a new algorithm for identifying inflammatory bowel disease patients in Denmark's national registry, finding it is more accurate than the currently used method.

  • 2023
    Exploring the Impact of Covid-19-Related Perceptions on Psychological Distress and Quality of Life in an International Gastrointestinal Cohort Over Time Guided by the Common Sense ModelSimon Robert Knowles, Stephan P. Möller, Andreas Stengel, Antonina A Mikocka‐Walus, Nuno Ferreira, Inês A. Trindade, Anna Mokrowiecka, Johan M. Burisch, Manuel Barreiro‐de Acosta, Charles Noah Bernstein, Bobby Zhao Sheng Lo, David Skvarc · Journal of Clinical Psychology in Medical Settings

    Tracking adults with gastrointestinal conditions during the pandemic, this study found a reciprocal relationship between gastrointestinal symptoms and psychological distress.

  • 2022
    Disease course and treatment outcomes of Crohn's disease patients with early or late surgery – A Danish nationwide cohort study from 1997 to 2015Melek Zahra Sarikaya, Mirabella Zhao, Bobby Zhao Sheng Lo, Flemming Bendtsen, Johan M. Burisch · Digestive and Liver Disease

    A study testing surgery timing in Crohn's disease patients found that undergoing surgery within 29 days of diagnosis reduced the risks of repeat surgery and subsequent medication use.

  • 2022
    The Incidence and Prevalence of Paediatric- and Adult-Onset Inflammatory Bowel Disease in Denmark During a 37-Year Period: A Nationwide Cohort Study (1980–2017)Maria Dorn‐Rasmussen, Bobby Zhao Sheng Lo, Mirabella Zhao, Gilaad G. Kaplan, Mikkel Malham, Vibeke Wewer, Johan M. Burisch · Journal of Crohn s and Colitis

    Researchers studying Inflammatory Bowel Disease (IBD) in Denmark found its incidence, for both children and adults, continuously rose to among the world's highest.

  • 2022
    Survey uncovering variations in the management of primary sclerosing cholangitis across EuropeJohanna Eliasson, Bobby Zhao Sheng Lo, Christoph Schramm, Olivier Chazouillères, Trine Folseraas, Ulrich H. Beuers, Henriette Ytting · JHEP Reports

    A survey of European hepatologists found significant variations in how primary sclerosing cholangitis patients are treated and monitored for related conditions.

  • 2022
    High Accuracy in Classifying Endoscopic Severity in Ulcerative Colitis Using Convolutional Neural NetworkBobby Zhao Sheng Lo, Zhuoyuan Liu, Flemming Bendtsen, Christian Igel, Ida Vind, Johan M. Burisch · The American Journal of Gastroenterology

    An AI model was developed and tested to automatically classify ulcerative colitis severity from endoscopic images, achieving high accuracy (up to 0.94) across different severity levels.

  • 2022
    Fear of COVID-19 Among Patients with Inflammatory Bowel Disease as Compared to Patients with Other Gastrointestinal ConditionsBobby Zhao Sheng Lo, Manuel Barreiro‐de Acosta, Charles Noah Bernstein, Johan M. Burisch, Nuno Bravo Ferreira, Richard Blair Gearry, Antonina A Mikocka‐Walus, Anna Mokrowiecka, Inês A. Trindade, Simon Robert Knowles · The Turkish Journal of Gastroenterology

    This study tested COVID-19 fear in IBD patients versus other GI conditions, finding IBD patients experienced more GI-specific fear, especially if on sick leave or in rural settings.

  • 2022
    P405 Primary non-response and loss-of-response to first-line biological therapies are more common in patients with Ulcerative Colitis than Crohn’s Disease – preliminary results from the Danish IBD Biobank ProjectMirabella Zhao, Lone Larsen, Anders Kirch Dige, Christian Lodberg Hvas, Anja Poulsen, D Christiansen, Mohamed Attauabi, Bobby Zhao Sheng Lo, Mads Damsgaard Wewer, Pernille Dige Ovesen, Andreas Munk Petersen, Flemming Bendtsen, Jakob Benedict Seidelin, Johan M. Burisch · Journal of Crohn s and Colitis

    Researchers investigated factors predicting biological drug failure in IBD patients, finding ulcerative colitis increased non-response and loss of response, but immunomodulators reduced risk.

  • 2021
    Extending the Common Sense Model to Explore the Impact of the Fear of COVID-19 on Quality of Life in an International Inflammatory Bowel Disease CohortBree Hayes, Pragalathan Apputhurai, Antonina A Mikocka‐Walus, Manuel Barreiro‐de Acosta, Charles Noah Bernstein, Rebecca Burgell, Johan M. Burisch, Floor Bennebroek Evertsz, Nuno Bravo Ferreira, Lesley A. Graff, Inês A. Trindade, Richard Blair Gearry, Bobby Zhao Sheng Lo, Anna Mokrowiecka, Gabriele Moser, Megan L. Petrik, Andreas Stengel, Simon Robert Knowles · Journal of Clinical Psychology in Medical Settings

    This study tested fear of COVID-19's impact on quality of life in IBD patients, finding it mediates GI symptom effects on QoL.

  • 2021
    Artificial intelligence assisted assessment of endoscopic disease activity in inflammatory bowel diseaseBobby Zhao Sheng Lo, Johan M. Burisch · Artificial Intelligence in Gastrointestinal Endoscopy

    Artificial intelligence was shown to assist in assessing endoscopic inflammatory bowel disease activity.

  • 2021
    The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative studyNuno Bravo Ferreira, Antonina A Mikocka‐Walus, Miranda A.L. van Tilburg, Lesley A. Graff, Pragalathan Apputhurai, Manuel Barreiro‐de Acosta, Floor Bennebroek Evertsz, Johan M. Burisch, Bobby Zhao Sheng Lo, Megan L. Petrik, Inês A. Trindade, Sharon Jedel, Gabriele Moser, Anna Mokrowiecka, Charles Noah Bernstein, Dan Lucian Dumitrascu, Alexander Charles Ford, Andreas Stengel, Richard Blair Gearry, Simon Robert Knowles · Journal of Psychosomatic Research

    This planned international study will evaluate the COVID-19 pandemic's impact on gastrointestinal symptoms and well-being in people with chronic GI disorders to guide targeted healthcare support.

  • 2021
    Histological Inflammation in the Endoscopically Uninflamed Mucosa is Associated With Worse Outcomes in Limited Ulcerative ColitisC Frias Gomes, Alexandra Sofia Ribeiro de Almeida, Catarina Callé Lucas Mendes, Pierre Ellul, Johan M. Burisch, Tiffany Buhagiar, Abigail Attard, Bobby Zhao Sheng Lo, Ryan C. Ungaro, B Morão, Catarina Ferreira Gouveia, Joana Milheiro Delgado de Carvalho e Branco, Jaime Rodrigues, Cristina Gomes de Oliveira Teixeira, M. Castro, Gonçalo Filipe Domingos Nunes, Mariana Brito, Marília Cristina de Sousa Antunes, Paula Borralho, Joana Torres · Inflammatory Bowel Diseases

    Testing newly diagnosed ulcerative colitis patients, researchers found that microscopic inflammation in normal-looking colon tissue predicts a higher risk of future complications and stronger treatment needs.

  • 2021
    Sa081 FEAR OF COVID-19 AMONG IBD PATIENTS ACCORDING TO EMPLOYMENT STATUS, EDUCATION AND RESIDENCE AND COMPARED TO OTHER GI CONDITIONSBobby Zhao Sheng Lo, Manuel Barreiro‐de Acosta, Charles Noah Bernstein, Johan M. Burisch, Nuno Bravo Ferreira, Richard Blair Gearry, Antonina A Mikocka‐Walus, Anna Mokrowiecka, Inês A. Trindade, Simon A. S. Knowles · Gastroenterology
  • 2021
    Su392 AN INTERNATIONAL STUDY ON WELL-BEING OF PATIENTS WITH GASTROINTESTINAL DISORDERS DURING THE COVID19 PANDEMICMiranda A.L. van Tilburg, Antonina A Mikocka‐Walus, Andreas Stengel, Inês A. Trindade, Gabriele Moser, Anna Mokrowiecka, Bobby Zhao Sheng Lo, Sharon Jedel, Nuno Bravo Ferreira, Dan L. Damitrascu, Johan M. Burisch, Floor Bennebroek Evertsz, Charles Noah Bernstein, Manuel Barreiro‐de Acosta, Simon Robert Knowles · Gastroenterology
  • 2021
    P162 Microscopic inflammation in limited Ulcerative Colitis at diagnosis: can a single histological feature predict prognosis?Joana Revés, C Frias Gomes, Pierre Ellul, Catarina Callé, Amanda Caroline Montelo Almeida, Johan M. Burisch, T Buhagiar, Abigail Attard, Bobby Zhao Sheng Lo, Ryan C. Ungaro, B Morão, Catarina Ferreira Gouveia, Joana C. Branco, Jaime Pereira Rodrigues, Cristina Gomes de Oliveira Teixeira, Francisca Dias de Castro, Gonçalo Filipe Domingos Nunes, María José Brito, Marília Cristina de Sousa Antunes, Joana Torres, Paula Borralho · Journal of Crohn s and Colitis

    Researchers tested single histological features in limited ulcerative colitis, finding neutrophils in over 50% of crypt epithelium predict higher disease complications.

  • 2021
    P610 Fear of COVID-19 among persons with Inflammatory Bowel Disease according to employment status, educational background and residential setting, as compared to persons with other gastrointestinal conditionsBobby Zhao Sheng Lo, Anna Mokrowiecka, Antonina A Mikocka‐Walus, Charles Noah Bernstein, Inês A. Trindade, Johan M. Burisch, Manuel Barreiro‐de Acosta, Nuno Bravo Ferreira, Richard Blair Gearry, Simon Robert Knowles · Journal of Crohn s and Colitis

    This study found people with Inflammatory Bowel Disease (IBD) had greater disease-specific COVID-19 fears than other gastrointestinal patients.

  • 2021
    OP07 Artificial intelligence surpasses gastrointestinal experts in the classification of endoscopic severity among Ulcerative ColitisBobby Zhao Sheng Lo, Zhong Liu, F Bendtsen, Christian Igel, Ida Vind, Johan M. Burisch · Journal of Crohn s and Colitis

    An AI model was tested on endoscopic images of ulcerative colitis patients and found to accurately distinguish different levels of disease activity.

  • 2020
    Systematic review of the prevalence and development of osteoporosis or low bone mineral density and its risk factors in patients with inflammatory bowel diseaseSofia Kärnsund, Bobby Zhao Sheng Lo, Flemming Bendtsen, Jakob Holm, Johan M. Burisch · World Journal of Gastroenterology

    This systematic review tested osteoporosis prevalence in IBD patients, finding Crohn's disease links to higher risk, especially with lower weight and BMI.

  • 2020
    Validation of ulcerative colitis and Crohn’s disease and their phenotypes in the Danish National Patient Registry using a population-based cohortBobby Zhao Sheng Lo, Ida Vind, Marianne Kajbæk Vester-Andersen, Johan M. Burisch · Scandinavian Journal of Gastroenterology

    Testing of the Danish National Patient Registry revealed it accurately identifies inflammatory bowel disease patients and their age at diagnosis, but is unreliable for detailed disease classification.

  • 2020
    The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort StudiesBobby Zhao Sheng Lo, Mirabella Zhao, Ida Vind, Johan M. Burisch · Clinical Gastroenterology and Hepatology
  • 2020
    Multistrain Probiotic Increases the Gut Microbiota Diversity in Obese Pregnant Women: Results from a Randomized, Double-Blind Placebo-Controlled StudySofie Ingdam Halkjær, Victoria Elizabeth de Knegt, Bobby Zhao Sheng Lo, Lisbeth Nilas, Dina Cortes, Anders Elm Pedersen, Hengameh Chloé Mirsepasi‐Lauridsen, Lee O’Brien Andersen, Henrik Vedel Nielsen, Christen Rune Stensvold, Thor Bech Johannesen, Thomas Kallemose, Karen Angeliki Krogfelt, Andreas Munk Petersen · Current Developments in Nutrition

    Daily probiotics in obese pregnant women did not affect weight gain, diabetes, or infant birth weight, but did modulate their gut microbiota.

  • 2020
    Fecal microbiota transplantation for treatment of irritable bowel syndromeSofie Ingdam Halkjær, Bobby Zhao Sheng Lo, Frederik Cold, Alice Hoejer H Christensen, Lise Lotte Gluud, Andreas Munk Petersen · Cochrane Database of Systematic Reviews

    This review will examine fecal microbiota transplantation versus placebo to determine benefits and harms for irritable bowel syndrome patients.

  • 2020
    Incidence, Risk Factors and Evaluation of Osteoporosis in Patients With Inflammatory Bowel Disease: A Danish Population-Based Inception Cohort With 10 Years of Follow-UpBobby Zhao Sheng Lo, Jakob Holm, Marianne Kajbæk Vester-Andersen, Flemming Bendtsen, Ida Vind, Johan M. Burisch · Journal of Crohn s and Colitis

    In IBD patients, osteoporosis incidence was significantly higher than controls, but bone density screening was infrequent.

  • 2020
    DOP43 The risk of extra-intestinal cancer in inflammatory bowel disease (IBD): A systematic review and meta-analysis of population-based cohort studiesBobby Zhao Sheng Lo, Mirabella Zhao, Ida Vind, Johan M. Burisch · Journal of Crohn s and Colitis

    This study found that patients with Crohn's disease and ulcerative colitis have an increased overall and site-specific risk of extra-intestinal cancers.

  • 2020
    Validation of ulcerative colitis and Crohn’s disease and their phenotypes in the Danish National Patient Registry using a population-based cohortBobby Zhao Sheng Lo, Ida Vind, Marianne Kajbæk Vester-Andersen, Johan M. Burisch · Figshare

    A study assessed the Danish National Patient Registry's reliability for IBD data, finding it good for identifying patients and age, but unreliable for detailed disease classification.

  • 2019
    Multi-strain Probiotic Increases the Gut Microbiota Diversity in Obese Pregnant Women: Results from a Randomized, Double-blind Placebo-controlled StudySofie Ingdam Halkjær, Victoria Elisabeth de Knegt, Bobby Zhao Sheng Lo, Lisbeth Nilas, Dina Cortes, Anders Elm Pedersen, Hengameh Chloé Mirsepasi‐Lauridsen, Lee O’Brien Andersen, Henrik Vedel Nielsen, Christen Rune Stensvold, Thor Bech Johannesen, Thomas Kallemose, Karen Angeliki Krogfelt, Andreas Munk Petersen · Unknown journal or conference

    Probiotic supplements were tested in obese pregnant women, showing they are feasible and can change gut bacteria, but did not significantly impact weight or diabetes.

  • 2019
    Paediatric onset inflammatory bowel disease is a distinct and aggressive phenotype:a comparative population‐based studyMikkel Malham, Christian Jakobsen, Marianne Kajbæk Vester-Andersen, Bobby Zhao Sheng Lo, Anders Pærregaard, Ida Vind, Vibeke Wewer · GastroHep

    GastroHep is an international, peer-reviewed journal published by Wiley that focuses on cutting-edge academic and clinical research in gastroenterology and hepatology.

  • 2019
    Paediatric onset inflammatory bowel disease is a distinct and aggressive phenotype—a comparative population‐based studyMikkel Malham, Christian Jakobsen, Marianne Kajbæk Vester-Andersen, Bobby Zhao Sheng Lo, Anders Pærregaard, Ida Vind, Vibeke Wewer · GastroHep

    This study tested paediatric versus adult IBD patients and found that children had more extensive disease, higher complication rates, and increased need for treatments and experienced more relapses.

  • 2019
    Health‐related quality of life in inflammatory bowel disease in a Danish population‐based inception cohortLea K Christiansen, Bobby Zhao Sheng Lo, Flemming Bendtsen, Ida Vind, Marianne Kajbæk Vester-Andersen, Johan M. Burisch · United European Gastroenterology Journal

    This study tested inflammatory bowel disease patients' quality of life, finding it similar to the general population, yet reduced by unemployment, sick leave, and disease activity.

  • 2019
    Direct and Indirect Costs of Inflammatory Bowel Disease: Ten Years of Follow-up in a Danish Population-based Inception CohortBobby Zhao Sheng Lo, Ida Vind, Marianne Kajbæk Vester-Andersen, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    This study assessed inflammatory bowel disease costs, finding direct costs high due to hospitalisation, but indirect costs did not exceed controls.

  • 2019
    DOP82 Direct and indirect costs of inflammatory bowel disease in the biological era; 10 years of follow-up in a Danish population-based inception cohortBobby Zhao Sheng Lo, Ida Vind, Morten Vester‐Andersen, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    This study assessed combined direct and indirect costs of inflammatory bowel disease, finding high direct costs but indirect costs similar to controls.

  • 2019
    P743 Bone mineral disease is insufficiently evaluated in patients with inflammatory bowel disease at risk of metabolic bone disease: results from a Danish population-based inception cohort studyBobby Zhao Sheng Lo, Ida Vind, Morten Vester‐Andersen, Jakob Holm, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    IBD patients face a higher osteoporosis risk, but this study found their bone density screening is inadequate, especially for those on steroid treatment.

  • 2018
    A 10-Year Follow-up Study of the Natural History of Perianal Crohn’s Disease in a Danish Population-Based Inception CohortMirabella Zhao, Bobby Zhao Sheng Lo, Marianne Kajbæk Vester-Andersen, Ida Vind, Flemming Bendtsen, Johan M. Burisch · Inflammatory Bowel Diseases

    A study on Crohn's patients revealed that perianal disease increases long-term risks of surgery and hospitalization, signaling a more severe disease course.

  • 2018
    Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled studySofie Ingdam Halkjær, Alice Højer Christensen, Bobby Zhao Sheng Lo, Patrick Denis Browne, Stig Günther, Lars Hestbjerg Hansen, Andreas Munk Petersen · Gut

    Fecal transplants changed gut bacteria in IBS patients, but placebo capsules led to greater symptom improvement.

  • 2018
    Disease activity, steroid use and extraintestinal manifestation are associated with increased disability in patients with inflammatory bowel disease using the inflammatory bowel disease disability index: a cross-sectional multicentre cohort studyBobby Zhao Sheng Lo, Mette Julsgaard, Marianne Kajbæk Vester-Andersen, Ida Vind, Johan M. Burisch · European Journal of Gastroenterology & Hepatology

    Researchers validated a Danish version of the inflammatory bowel disease disability index, finding that Crohn's disease, active illness, and steroid use are linked to higher disability.

  • 2018
    914 - Fecal Microbiota Transplantation Alters Gut Microbiota in Patients with Irritable Bowel Syndrome: Results from a Randomized, Double-Blind Placebo Controlled StudySofie Ingdam Halkjær, Alice Christensen, Bobby Zhao Sheng Lo, Patrick J. Browne, Stig Günther, Lars Hestbjerg Hansen, Andreas Munk Petersen · Gastroenterology
  • 2018
    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsiesMette Boyd, Malte Thodberg, Morana Vitezic, Jette Bornholdt, Kristoffer Vitting‐Seerup, Yun Chen, Mehmet Yavuz Coşkun, Yuan Li, Bobby Zhao Sheng Lo, Pia Helene Klausen, Pawel J. Schweiger, Anders Gorm Pedersen, Nicolas Rapin, Kerstin Skovgaard, Katja Dahlgaard, Robin Andersson, Thilde Terkelsen, Berit Lilje, Jesper Thorvald Troelsen, Andreas Munk Petersen, Kim Bak Jensen, Ismail Gögenür, Peter Thielsen, Jakob Benedict Seidelin, Ole Haagen Nielsen, Jacob Tveiten Bjerrum, Albin Sandelin · Nature Communications

    By profiling colon tissue from 94 people, researchers found that just 35 gene-regulating sites can distinguish Crohn’s disease, ulcerative colitis, and healthy controls with 85% accuracy.

  • 2018
    DOP041 Surgery and hospitalisation in patients with inflammatory bowel disease; 10-year follow-up of a Danish population-based inception cohortBobby Zhao Sheng Lo, Ida Vind, Flemming Bendtsen, Morten Vester‐Andersen, Johan M. Burisch · Journal of Crohn s and Colitis

    This study found that despite new treatments, the risk of surgery and hospitalisation for inflammatory bowel disease remains high.

  • 2018
    P813 Occurrence, disease course and prognosis of perianal Crohn’s disease in a Danish population-based inception cohort—a 10-year follow-up studyMirabella Zhao, Bobby Zhao Sheng Lo, Morten Vester‐Andersen, Ida Vind, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    This study tested risk factors for perianal Crohn's disease and found colon involvement and penetrating disease predict its development, leading to more surgery and hospitalizations.

  • 2018
    P786 The use and escalation of treatments in patients with inflammatory bowel disease; a 10 years follow-up of a Danish population-based inception cohortBobby Zhao Sheng Lo, Ida Vind, Flemming Bendtsen, Morten Vester‐Andersen, Johan M. Burisch · Journal of Crohn s and Colitis

    Researchers studied IBD treatment changes over 10 years, finding Crohn's patients more often needed advanced therapies than UC patients.

  • 2017
    Systematic review and meta‐analysis: assessment of factors affecting disability in inflammatory bowel disease and the reliability of the inflammatory bowel disease disability indexBobby Zhao Sheng Lo, Michelle V. Prosberg, Lise Lotte Gluud, Webber Pak Wo Chan, Rupert Wing Loong Leong, Ellie van der List, Mike van der Have, Hélène Sarter, C. Gower‐Rousseau, Laurent Peyrin‐Biroulet, Ida Vind, Johan M. Burisch · Alimentary Pharmacology & Therapeutics

    This review tested the Inflammatory Bowel Disease Disability Index and found it a reliable tool, showing active disease increases disability while biological treatments decrease it.

  • 2017
    Changes in Disease Behaviour and Location in Patients With Crohn’s Disease After Seven Years of Follow-Up: A Danish Population-based Inception CohortBobby Zhao Sheng Lo, Morten Vester‐Andersen, Ida Vind, Michelle V. Prosberg, Marla C. Dubinsky, Corey Allan Siegel, Flemming Bendtsen, Johan M. Burisch · Journal of Crohn s and Colitis

    Changing disease location or behavior predicted worse Crohn's disease outcomes, while biologics helped prevent location changes.

  • 2008
    Social media analytics in business intelligence applicationsBobby Zhao Sheng Lo · DSpace@MIT (Massachusetts Institute of Technology)

    This MIT M. Eng. thesis record provides no details on tested methods or research findings.