- 2026Changes in nasal and throat microbiota composition during and after mupirocin and chlorhexidine decolonization treatment in asymptomatic methicillin-resistant Staphylococcus aureus carriers: a longitudinal observational study
Testing a standard MRSA decolonization treatment showed that while it successfully cleared the bacteria in most carriers, it also caused long-lasting disruptions to their nasal microbiomes.
- 2026Forecasting the Incidence and Prevalence of Inflammatory Bowel Disease Across Nine Epidemiologic Stage 3 Regions
Highlighted publications
- 2018Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study
Fecal transplants changed gut bacteria in IBS patients, but placebo capsules led to greater symptom improvement.
- 2025Global evolution of inflammatory bowel disease across epidemiologic stages
By analyzing a century of data from 522 global studies, researchers mapped the real-world progression of inflammatory bowel disease, confirming its transition through four previously theoretical epidemiological stages.
- 2018Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
By profiling colon tissue from 94 people, researchers found that just 35 gene-regulating sites can distinguish Crohn’s disease, ulcerative colitis, and healthy controls with 85% accuracy.
- 2020The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort Studies
- 2018A 10-Year Follow-up Study of the Natural History of Perianal Crohn’s Disease in a Danish Population-Based Inception Cohort
A study on Crohn's patients revealed that perianal disease increases long-term risks of surgery and hospitalization, signaling a more severe disease course.
Peer-reviewed publications
- 2025AI-BUS: AI Bowel Ultrasound System
- 2025Clinical Trial: Evaluating a Single 1600 mg Tablet Regimen of 5‐Aminosalicylate for Ulcerative Colitis—The <scp>EASI</scp> Trial
A clinical trial comparing a single daily tablet for ulcerative colitis to three tablets found that both treatments resulted in similar patient adherence and disease relapse rates.
- 2025Incidence and Long‐Term Outcomes of Pouchitis in Ulcerative Colitis Patients
A study of ulcerative colitis patients after pouch surgery found that half experienced pouchitis, but urgent surgery did not increase this risk, and overall pouch failure was low.
- 2025The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative study
- 202549: THE INCIDENCE AND PREVALENCE OF INFLAMMATORY BOWEL DISEASE IN NINE NATIONS ACROSS THE GLOBE: AN ANALYSIS OF THE 3RD EPIDEMIOLOGIC STAGE.
- 2025Global evolution of inflammatory bowel disease across epidemiologic stages
By analyzing a century of data from 522 global studies, researchers mapped the real-world progression of inflammatory bowel disease, confirming its transition through four previously theoretical epidemiological stages.
- 2025Improving the Real-Time Classification of Disease Severity in Ulcerative Colitis: Artificial Intelligence as the Trigger for a Second Opinion
An AI system tested for classifying ulcerative colitis severity from endoscopy videos matched expert accuracy and improved the diagnostic performance of non-specialist doctors.
- 2025P0290 Predicting disease remission in Ulcerative Colitis patients - early results from the PRESAGER study
This study analyzed predictors of ulcerative colitis remission, finding that older age and higher disability reduced its likelihood, while longer disease duration and moderate activity increased it.
- 2024Clinical Outcomes After First-Line Anti- Tumor-Necrosis-Factor Treatment of Patients With Inflammatory Bowel Disease—A Prospective Multicenter Cohort Study
Testing anti-TNF therapy in patients with inflammatory bowel disease showed that while most responded initially, about a quarter to a third eventually lost response during maintenance therapy.
- 2024Histological, But Neither Clinical Nor Endoscopic Activity Predicts the Risk of Colectomy in Patients With Ulcerative Colitis Treated With Biologics
A study of ulcerative colitis patients starting biological therapy found that severe baseline tissue inflammation, but not endoscopic activity, independently predicts a higher risk of colon removal.
- 2024Probiotic Treatment of Ulcerative Colitis with <i>Trichuris Suis</i> Ova: A Randomised, Double-blinded, Placebo-controlled Clinical Trial [the PROCTO Trial]
A clinical trial testing Trichuris suis ova for moderate ulcerative colitis found that the treatment was not superior to placebo in achieving clinical remission at 24 weeks.
- 2024Building an AI Support Tool for Real-Time Ulcerative Colitis Diagnosis
- 2024Specific Antibiotics Increase the Risk of Flare-Ups in Patients with Inflammatory Bowel Disease: Results from a Danish Nationwide Population-Based Nested Case-Control Study
A study of Danish patients found that using specific classes of antibiotics is associated with a significantly increased risk of inflammatory bowel disease flare-ups.
- 2024The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic Stages
Analyzing a century of global data, researchers mapped how inflammatory bowel disease transitions through distinct epidemiological stages, confirming its progression from low incidence to compounding prevalence.
- 2024P1240 Systematic review with meta-analysis: faecal microbiota transplantation as treatment of chronic pouchitis
A systematic review found that fecal microbiota transplantation was no more effective than a placebo at improving short-term symptoms in patients with chronic pouchitis.
- 2024P375 Histological activity predicts the risk of colectomy after biological treatment in biological-naive patients with Ulcerative Colitis
Testing ulcerative colitis patients starting biological therapy, researchers found that baseline gut tissue inflammation significantly predicted the risk of colon removal, while clinical and endoscopic symptoms did not.
- 2024P1174 The disease course of elderly patients with Inflammatory Bowel Disease two years prior to their death
By examining elderly inflammatory bowel disease patients before death, researchers found that hospitalizations, corticosteroid prescriptions, and disease relapses spiked during the final two months of life.
- 2024P598 Validating and Enhancing Real-time Disease Severity Classification in Ulcerative Colitis: Artificial Intelligence as a Second Opinion Trigger
An AI model tested for evaluating ulcerative colitis severity from endoscopy videos matched expert accuracy and improved the diagnostic performance of non-specialist doctors.
- 2023Fecal microbiota transplantation for the treatment of irritable bowel syndrome: A systematic review and meta-analysis
A review of fecal microbiota transplantation for irritable bowel syndrome found insufficient evidence to support its use, as it did not significantly improve symptoms compared to a placebo.
- 2023Tu1715 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL ON EFFICACY AND SAFETY OF PROBIOTIC TREATMENT WITH TRICHURIS SUIS OVA IN PATIENTS WITH ULCERATIVE COLITIS
- 2023Identifying patients with inflammatory bowel disease in the Danish National Patient Register.
Researchers tested a new algorithm for identifying inflammatory bowel disease patients in Denmark's national registry, finding it is more accurate than the currently used method.
- 2023Exploring the Impact of Covid-19-Related Perceptions on Psychological Distress and Quality of Life in an International Gastrointestinal Cohort Over Time Guided by the Common Sense Model
Tracking adults with gastrointestinal conditions during the pandemic, this study found a reciprocal relationship between gastrointestinal symptoms and psychological distress.
- 2022Disease course and treatment outcomes of Crohn's disease patients with early or late surgery – A Danish nationwide cohort study from 1997 to 2015
A study testing surgery timing in Crohn's disease patients found that undergoing surgery within 29 days of diagnosis reduced the risks of repeat surgery and subsequent medication use.
- 2022The Incidence and Prevalence of Paediatric- and Adult-Onset Inflammatory Bowel Disease in Denmark During a 37-Year Period: A Nationwide Cohort Study (1980–2017)
Researchers studying Inflammatory Bowel Disease (IBD) in Denmark found its incidence, for both children and adults, continuously rose to among the world's highest.
- 2022Survey uncovering variations in the management of primary sclerosing cholangitis across Europe
A survey of European hepatologists found significant variations in how primary sclerosing cholangitis patients are treated and monitored for related conditions.
- 2022High Accuracy in Classifying Endoscopic Severity in Ulcerative Colitis Using Convolutional Neural Network
An AI model was developed and tested to automatically classify ulcerative colitis severity from endoscopic images, achieving high accuracy (up to 0.94) across different severity levels.
- 2022Fear of COVID-19 Among Patients with Inflammatory Bowel Disease as Compared to Patients with Other Gastrointestinal Conditions
This study tested COVID-19 fear in IBD patients versus other GI conditions, finding IBD patients experienced more GI-specific fear, especially if on sick leave or in rural settings.
- 2022P405 Primary non-response and loss-of-response to first-line biological therapies are more common in patients with Ulcerative Colitis than Crohn’s Disease – preliminary results from the Danish IBD Biobank Project
Researchers investigated factors predicting biological drug failure in IBD patients, finding ulcerative colitis increased non-response and loss of response, but immunomodulators reduced risk.
- 2021Extending the Common Sense Model to Explore the Impact of the Fear of COVID-19 on Quality of Life in an International Inflammatory Bowel Disease Cohort
This study tested fear of COVID-19's impact on quality of life in IBD patients, finding it mediates GI symptom effects on QoL.
- 2021Artificial intelligence assisted assessment of endoscopic disease activity in inflammatory bowel disease
Artificial intelligence was shown to assist in assessing endoscopic inflammatory bowel disease activity.
- 2021The impact of the coronavirus (COVID-19) pandemic on individuals with gastrointestinal disorders: A protocol of an international collaborative study
This planned international study will evaluate the COVID-19 pandemic's impact on gastrointestinal symptoms and well-being in people with chronic GI disorders to guide targeted healthcare support.
- 2021Histological Inflammation in the Endoscopically Uninflamed Mucosa is Associated With Worse Outcomes in Limited Ulcerative Colitis
Testing newly diagnosed ulcerative colitis patients, researchers found that microscopic inflammation in normal-looking colon tissue predicts a higher risk of future complications and stronger treatment needs.
- 2021P610 Fear of COVID-19 among persons with Inflammatory Bowel Disease according to employment status, educational background and residential setting, as compared to persons with other gastrointestinal conditions
This study found people with Inflammatory Bowel Disease (IBD) had greater disease-specific COVID-19 fears than other gastrointestinal patients.
- 2021OP07 Artificial intelligence surpasses gastrointestinal experts in the classification of endoscopic severity among Ulcerative Colitis
An AI model was tested on endoscopic images of ulcerative colitis patients and found to accurately distinguish different levels of disease activity.
- 2021Sa081 FEAR OF COVID-19 AMONG IBD PATIENTS ACCORDING TO EMPLOYMENT STATUS, EDUCATION AND RESIDENCE AND COMPARED TO OTHER GI CONDITIONS
- 2021Su392 AN INTERNATIONAL STUDY ON WELL-BEING OF PATIENTS WITH GASTROINTESTINAL DISORDERS DURING THE COVID19 PANDEMIC
- 2021P162 Microscopic inflammation in limited Ulcerative Colitis at diagnosis: can a single histological feature predict prognosis?
Researchers tested single histological features in limited ulcerative colitis, finding neutrophils in over 50% of crypt epithelium predict higher disease complications.
- 2020Systematic review of the prevalence and development of osteoporosis or low bone mineral density and its risk factors in patients with inflammatory bowel disease
This systematic review tested osteoporosis prevalence in IBD patients, finding Crohn's disease links to higher risk, especially with lower weight and BMI.
- 2020Validation of ulcerative colitis and Crohn’s disease and their phenotypes in the Danish National Patient Registry using a population-based cohort
Testing of the Danish National Patient Registry revealed it accurately identifies inflammatory bowel disease patients and their age at diagnosis, but is unreliable for detailed disease classification.
- 2020The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort Studies
- 2020Multistrain Probiotic Increases the Gut Microbiota Diversity in Obese Pregnant Women: Results from a Randomized, Double-Blind Placebo-Controlled Study
Daily probiotics in obese pregnant women did not affect weight gain, diabetes, or infant birth weight, but did modulate their gut microbiota.
- 2020Fecal microbiota transplantation for treatment of irritable bowel syndrome
This review will examine fecal microbiota transplantation versus placebo to determine benefits and harms for irritable bowel syndrome patients.
- 2020Incidence, Risk Factors and Evaluation of Osteoporosis in Patients With Inflammatory Bowel Disease: A Danish Population-Based Inception Cohort With 10 Years of Follow-Up
In IBD patients, osteoporosis incidence was significantly higher than controls, but bone density screening was infrequent.
- 2020DOP43 The risk of extra-intestinal cancer in inflammatory bowel disease (IBD): A systematic review and meta-analysis of population-based cohort studies
This study found that patients with Crohn's disease and ulcerative colitis have an increased overall and site-specific risk of extra-intestinal cancers.
- 2020Validation of ulcerative colitis and Crohn’s disease and their phenotypes in the Danish National Patient Registry using a population-based cohort
A study assessed the Danish National Patient Registry's reliability for IBD data, finding it good for identifying patients and age, but unreliable for detailed disease classification.
- 2019Multi-strain Probiotic Increases the Gut Microbiota Diversity in Obese Pregnant Women: Results from a Randomized, Double-blind Placebo-controlled Study
Probiotic supplements were tested in obese pregnant women, showing they are feasible and can change gut bacteria, but did not significantly impact weight or diabetes.
- 2019Paediatric onset inflammatory bowel disease is a distinct and aggressive phenotype—a comparative population‐based study
This study tested paediatric versus adult IBD patients and found that children had more extensive disease, higher complication rates, and increased need for treatments and experienced more relapses.
- 2019Health‐related quality of life in inflammatory bowel disease in a Danish population‐based inception cohort
This study tested inflammatory bowel disease patients' quality of life, finding it similar to the general population, yet reduced by unemployment, sick leave, and disease activity.
- 2019Direct and Indirect Costs of Inflammatory Bowel Disease: Ten Years of Follow-up in a Danish Population-based Inception Cohort
This study assessed inflammatory bowel disease costs, finding direct costs high due to hospitalisation, but indirect costs did not exceed controls.
- 2019DOP82 Direct and indirect costs of inflammatory bowel disease in the biological era; 10 years of follow-up in a Danish population-based inception cohort
This study assessed combined direct and indirect costs of inflammatory bowel disease, finding high direct costs but indirect costs similar to controls.
- 2019P743 Bone mineral disease is insufficiently evaluated in patients with inflammatory bowel disease at risk of metabolic bone disease: results from a Danish population-based inception cohort study
IBD patients face a higher osteoporosis risk, but this study found their bone density screening is inadequate, especially for those on steroid treatment.
- 2018A 10-Year Follow-up Study of the Natural History of Perianal Crohn’s Disease in a Danish Population-Based Inception Cohort
A study on Crohn's patients revealed that perianal disease increases long-term risks of surgery and hospitalization, signaling a more severe disease course.
- 2018Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study
Fecal transplants changed gut bacteria in IBS patients, but placebo capsules led to greater symptom improvement.
- 2018Disease activity, steroid use and extraintestinal manifestation are associated with increased disability in patients with inflammatory bowel disease using the inflammatory bowel disease disability index: a cross-sectional multicentre cohort study
Researchers validated a Danish version of the inflammatory bowel disease disability index, finding that Crohn's disease, active illness, and steroid use are linked to higher disability.
- 2018914 - Fecal Microbiota Transplantation Alters Gut Microbiota in Patients with Irritable Bowel Syndrome: Results from a Randomized, Double-Blind Placebo Controlled Study
- 2018Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
By profiling colon tissue from 94 people, researchers found that just 35 gene-regulating sites can distinguish Crohn’s disease, ulcerative colitis, and healthy controls with 85% accuracy.
- 2018DOP041 Surgery and hospitalisation in patients with inflammatory bowel disease; 10-year follow-up of a Danish population-based inception cohort
This study found that despite new treatments, the risk of surgery and hospitalisation for inflammatory bowel disease remains high.
- 2018P786 The use and escalation of treatments in patients with inflammatory bowel disease; a 10 years follow-up of a Danish population-based inception cohort
Researchers studied IBD treatment changes over 10 years, finding Crohn's patients more often needed advanced therapies than UC patients.
- 2018P813 Occurrence, disease course and prognosis of perianal Crohn’s disease in a Danish population-based inception cohort—a 10-year follow-up study
This study tested risk factors for perianal Crohn's disease and found colon involvement and penetrating disease predict its development, leading to more surgery and hospitalizations.
- 2017Systematic review and meta‐analysis: assessment of factors affecting disability in inflammatory bowel disease and the reliability of the inflammatory bowel disease disability index
This review tested the Inflammatory Bowel Disease Disability Index and found it a reliable tool, showing active disease increases disability while biological treatments decrease it.
- 2017Changes in Disease Behaviour and Location in Patients With Crohn’s Disease After Seven Years of Follow-Up: A Danish Population-based Inception Cohort
Changing disease location or behavior predicted worse Crohn's disease outcomes, while biologics helped prevent location changes.
- 2008Social media analytics in business intelligence applications
This MIT M. Eng. thesis record provides no details on tested methods or research findings.